Healthcare Professional View

Bone Cement | Fillers

Jindal Medi Surge [JMS] Bone cement and bone fillers are materials used in orthopedic and dental procedures to stabilize, support, or fill bone defects. They serve different purposes in various medical applications. Here's an overview of bone cement and fillers: Bone Cement: Purpose: Bone cement, often referred to as polymethylmethacrylate (PMMA), is commonly used in orthopedic procedures, such as joint replacements (e.g., hip and knee replacements). Composition: PMMA bone cement is a mixture of a powder (typically polymethylmethacrylate beads) and a liquid monomer (methyl methacrylate). Application: In joint replacement surgery, bone cement is used to fix prosthetic components to the existing bone. It provides stability and helps distribute loads between the implant and the surrounding bone. Setting Process: The powder and liquid are mixed to form a dough-like consistency, which is then applied to the bone. It undergoes an exothermic polymerization reaction, hardening into a solid mass. Bone Fillers: Purpose: Bone fillers are materials used to fill bone voids or defects. They promote bone regeneration and healing. Types: Autografts: Bone harvested from the patient's own body. Allografts: Donor bone from another individual, often cadaveric bone. Synthetic Fillers: Various synthetic materials, including ceramics, hydroxyapatite, tricalcium phosphate, and bioactive glasses. Demineralized Bone Matrix (DBM): Allograft bone that has been processed to retain growth factors. Bone Morphogenetic Proteins (BMPs): Recombinant proteins that stimulate bone formation. Applications: Bone fillers are used in various procedures, including bone grafting, spinal fusion, and treatment of bone cysts or defects. Biodegradability: Some bone fillers are designed to be gradually resorbed by the body as new bone tissue forms. Calcium Phosphate Cement: Purpose: Calcium phosphate cements are synthetic bone substitutes that can be used as injectable fillers for bone defects. Composition: Composed of calcium and phosphate compounds. Setting Process: Undergo a setting reaction in situ, transforming from a paste to a hardened material. Applications: Used in various orthopedic and dental applications, particularly in minimally invasive procedures. Hydroxyapatite Fillers: Purpose: Hydroxyapatite is a naturally occurring mineral that is used as a bone filler. It is often incorporated into synthetic bone graft materials. Composition: Similar to the mineral component of natural bone. Applications: Used in dental and orthopedic surgeries to fill bone defects and promote bone regeneration. The choice between bone cement and bone fillers depends on the specific clinical scenario, the nature of the procedure, and the surgeon's preferences. In some cases, a combination of bone cement and fillers may be used to achieve the desired outcome, such as in joint replacement surgeries with additional bone grafting for defect augmentation.